Richard Hughes will take over the reins on leading fancy Keys in Saturday's Betfred Cesarewitch at Newmarket.
Jamie Spencer guided the four-year-old to July victories at Newbury and Ascot, but he is due to ride Dance And Dance in America on the same day and so is unavailable.
Trainer Roger Charlton confirmed Hughes' appointment via Twitter.
Keys' participation had been in some doubt over the weekend following a dirty scope, but Charlton issued an upbeat bulletin on his condition on Monday.
David Pipe also used the social networking site to reveal jockey plans for his three contenders, with William Buick booked for Beyond, Joseph O'Brien taking the mount of Tasheba and apprentice Kieran O'Neill called up for Big Occasion.
Pipe's father Martin saddled Heros Fatal (2000) and Miss Fara (2002) to win the famous staying handicap in recent years.
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