Kieren Fallon has been booked by Mark Johnston to ride Jukebox Jury, who was well behind Dar Re Mi in Dubai and has struggled in other domestic Group One events despite thriving abroad.
Fallon has won the Eclipse twice before, aboard Medicean in 2001 and Oratorio in 2005.
"Jukebox Jury may have finished one place ahead of Twice Over in last year's Coral-Eclipse, but the betting suggests that Kieren Fallon will need to be at his very best to confirm that running on Saturday," said Coral's David Stevens.
William Buick has needed to wait a while, but he will finally get his second chance to ride Dar Re Mi.
John Gosden's mare, owned by Andrew Lloyd Webber, has already mixed it with the very best in middle-distance company and is second favourite behind Twice Over for the Sandown Group One.
Fifth to Sea The Stars in last year's Prix de l'Arc de Triomphe and third to Conduit in the Breeders' Cup Turf, Dar Re Mi returned this year with victory in the Dubai Sheema Classic.
Rising star Buick had not long been appointed stable jockey to the powerful Gosden operation and netting the near-£2million contest was a dream start for the partnership in late March.
Dar Re Mi has missed a couple of options and steps back onto the course against the likes of Prince of Wales's Stakes runner-up Twice Over and Zacinto, who steps up from a mile for the first time.
Buick said: "She's a stable star, an exceptional filly. What she did in Dubai was top class and it was a great experience for me.
"She is back down to a mile and a quarter for the first time in a while but I think she has a good chance."
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